The ruins of Colossae have yet to be excavated, even though scholars have located the ancient site. This video shows Colossae’s location in relation to Ephesus, the most important city in the region. Ephesus was 120 miles (200 km) due west of Colossae through the well-traveled Lycus River Valley. The Lycus merges into the Meander River closer to Ephesus. Colossae was located at the base of Mt. Cadmus, which gave a constant source of cool, refreshing water to the city. When earthquakes destroyed the city, the Romans allowed Colossae to diminish. Nearby Laodicea and Hierapolis became larger and more important communities on the trade route. Paul’s letter to the Colossians mentions both of those towns (Colossians 4:13).